Postdoctoral Research Associate - Immunology

St. Jude Children's Research Hospital is committed to the education and training of the next generation of research scientists. St. Jude trainees are able to learn from clinical and basic science investigators who work in close proximity and interact regularly to translate scientific discoveries into improved therapies for children. If you are a highly motivated individual who wants to work at a world-class institution with state-of-the-art facilities and learn from investigators at the forefront of their fields, consider advancing your research training at St. Jude.

We are particularly interested in dissecting the signaling pathways involved in innate immune responses and cell death (NLRs, caspases, inflammasomes, and inflammatory cell death, PANoptosis) and understanding how these pathways connect to adaptive immunity (T cells). Please see the following articles:

Cell (2023) 186(13):2783-801.e20.

Science Immunology (2022) 7(74):eabo6294.

Nature (2021) 597(7876):415-9.Cell (2021) 184(1)_149-168.e17.

Cell (2020) 181(3):674-687.e13.

Nature (2019) 573(7775):590-4.

Nature Microbiology (2019) 4(2):316-27.

Cell (2018) 173:1–14.

Journal of Experimental Medicine (2018) 215(4):1023-34.

Nature (2016) 540:583-7.

Science Immunology (2016) 1(2):aag204-5.

The ideal candidate will have experience with immunology or cell/molecular biology methodologies, such as:

Macrophage and primary cell culture

T cell analyses

Western blotting

qPCR

CRISPR

Co-immunoprecipitation experiments

The laboratory of Dr. Thirumala-Devi Kanneganti offers a remarkable training environment for postdoctoral fellows focused on the innate immune system and its connections with adaptive immunity, including an opportunity to collaborate with researchers in the departments of Immunology, Host Microbe Interactions, and cancer biology. Generous salary support and a benefits package that includes professional development funds for journal subscriptions and travel to meetings are available. St. Jude Children's Research Hospital has state-of-the-art facilities including core laboratories for proteomics, metabolomics, RNAseq, transgenic/knock-out technology, and animal facilities from biosafety level 2 to enhanced biosafety level 3.

Candidates should have a recent PhD, DVM, MD/PhD in biomedical sciences with practical experience in immunology (innate and adaptive immune responses) and must be hard working and highly motivated.