Early Development Program Lead – Cambridge

In this role, you’ll have the opportunity to serve as the primary bridge between the Cambridge Research organization and Insmed's Development functions; lead and coordinate cross-functional early development project teams spanning medicinal chemistry, CMC, formulation, biology, toxicology, DMPK/ADME, translational science, regulatory, clinical, and patient advocacy. You’ll also:

Project Leadership

Provide strategic scientific project leadership and oversight for the cross-functional team to spearhead the definition of project objectives.

Lead the definition and oversee execution of the scientific strategy for assigned small molecule and/or ASO programs, from late lead optimization up to IND.

Establish productive working relationships with CROs and CDMOs to ensure timely completion of outsourced activities, partnering with relevant Insmed functions to identify, assess, and oversee.

Integrate multi-disciplinary data to drive candidate selection decisions aligned with the Target Product Profile (TPP).

Facilitate resource allocation and decision-making across functions with competing priorities and timelines.

Set ambition and define & drive project strategy through key milestones; accountable for project timeline and execution to facilitate meeting deliverables necessary for project continuation.

Lead identification and management of key risks across scientific, CMC, and clinical domains, including appropriate mitigation and contingency planning.

Project Management

Work with Program Management to develop, maintain, and communicate integrated project plans, timelines, budgets, and risk registers.

Lead cross functional discussions to develop early TPPs.

Facilitate team meetings, drive decision-making, and ensure accountability across functions; prepare and present program updates to senior leadership and governance committees.

Proactively identify and communicate risks and develop mitigation strategies to keep programs on track.

Collaborate with portfolio management to ensure alignment with corporate strategy.