We are seeking a Staff Machine Learning Scientist – Translational AI to provide technical leadership at the intersection of deep learning foundation models, computational biology, and molecular diagnostics.
This ownership role drives the architecture and validation of genomic, transcriptomic, and multimodal sequence models to accelerate patient stratification, target identification, and therapeutic monitoring across our cell-free DNA (cfDNA) and multi-omic platforms.
This Staff-level position operates with broad technical autonomy, driving modeling strategy across multiple concurrent portfolios while maintaining direct execution responsibilities in model compilation, scaling, and testing.
Working within a builder framework, you will align across AI Research, Bioinformatics, and Clinical Science divisions to transition advanced representation learning models into reproducible, clinically valid diagnostic assets.
Key Skills for This Role
huggingfacemlflowpytorch
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QUALIFICATIONS:
PhD in Computer Science, Computational Biology, Bioinformatics, Biomedical Engineering, or a highly quantitative structural field
5+ years of industry or post-doctoral experience applying deep learning frameworks to complex biological, genomic, or clinical datasets, with a documented focus on oncology or immunology portfolios
Deep technical competency with transformer architectures, representation learning, self-supervised learning (SSL), or deep sequence modeling
Proven track record of translating machine learning outputs into verifiable biological variables or clinical performance indicators, rather than optimizing solely for isolated cross-validation metrics
Expert proficiency in PyTorch and modern machine learning infrastructure (e.g., HuggingFace ecosystem, PEFT, Captum, MLflow, and distributed GPU computing setups)
Documented technical leadership through end-to-end project ownership, architectural design authority, or cross-functional team direction
Preferred Qualifications:
Experience constructing or fine-tuning multimodal foundation models that combine high-depth genomic sequencing data with digital pathology images or longitudinal electronic health records (EHR)
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KNOWLEDGE, SKILLS, AND ABILITIES:
Advanced mathematical and algorithmic fluency across deep learning methodologies, optimization strategies, and probabilistic modeling
Fast learner with the capability to master complex cfDNA platforms, biochemistry workflows, and multi-omic data generation pipelines rapidly
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OUR OPPORTUNITY
NateraTM is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.
The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
WHAT WE OFFER
Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!
For more information, visit www.natera.com.
Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.
All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, age, veteran status, disability or any other legally protected status. We also consider qualified applicants regardless of criminal histories, consistent with applicable laws.
If you are based in California, we encourage you to read this important information for California residents.
Please be advised that Natera will reach out to candidates with a @ natera.com email domain ONLY. Email communications from all other domain names are not from Natera or its employees and are fraudulent. Natera does not request interviews via text messages and does not ask for personal information until a candidate has engaged with the company and has spoken to a recruiter and the hiring team. Natera takes cyber crimes seriously, and will collaborate with law enforcement authorities to prosecute any related cyber crimes.
For more information: - BBB announcement on job scams - FBI Cyber Crime resource page
About Natera
Pharmaceuticals & Biotech
Genetic testing company specializing in cell-free DNA diagnostics for oncology, women's health, and organ transplant monitoring.