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Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.
Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.
If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.
We are currently looking for a high-performing Senior Software Engineer, Prenatal to join our dynamic software engineering team. Software engineers at BillionToOne work in highly collaborative and interdisciplinary teams of clinicians, computational biologists, and other engineers to robustly scale personalized genomic medicine to millions of patients. If you have experience performing in a full life-cycle development, love seeing your work positively affect your colleagues and patients, and thrive in a fast-paced entrepreneurial environment, this could be a great opportunity for you. In this role, you can have an impact both through many small tools and large product development. This role is a hybrid (onsite 2-3 days/week) position.
Projects you may work on include:
Scaling and future-proofing core systems to support rapid volume growth, enterprise workloads, and long-term platform expansion.
Building shared platform libraries and modular, domain-aligned services that reduce coupling, improve maintainability, and enable teams to integrate and deliver independently.
Driving core architectural initiatives including service boundaries, data flows, observability patterns, and modernization of legacy components to enhance reliability and developer velocity.
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Unity CompleteTM is the only non-invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample. Unity ConfirmTM enables non-invasive confirmation for high-risk screening results through the capture of intact circulating fetal cells using BillionToOne’s Fetal Cell CaptureTM Technology. Our Northstar® liquid biopsy test uniquely combines treatment selection with real-time monitoring, giving oncologists unprecedented precision in cancer care.
From $0 to $400M+ annualized revenue run-rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world-class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.
Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified, with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.
Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.
Ready to help us change the world, one molecule at a time? Learn more at billiontoone.com
Precision diagnostics company whose patented molecular counting technology enables highly accurate prenatal screening and liquid biopsy tests at the single-molecule level.
Visit company websiteJobs and hiring trendsUSD 192932-214369 / year
Senior · 5–7 years experience
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