Senior Research Associate Biochemistry

What you will do:

• Plans and performs experiments as described in protocols and improves upon these protocols. Is able to apply protocols beyond the original scope.
• Plans and executes enzymatic and chemical reactions on antibodies and other proteins and trouble-shoots where appropriate. Performs various laboratory techniques for protein purification (protein A chromatography, SEC and IEX) and characterization (SDS-PAGE, RP‐UPLC, SE-UPLC, UPLC‐MS) and critically assesses the results.
• Plans and executes functional analyses including cell-based assays (in vitro cytotoxicity, reporter cell lines) and ELISA-based assays and critically assesses the results. Coordinates biological assays outsourced to a CRO (e.g. communication with CRO, coordinating shipments and drafting study protocols).
• Collects experimental data, interprets the results, draws conclusions and proposes next steps to the supervisor. Prepares slides/presentations for internal and external use. Prepares and writes examples for IP filing.
• Is accountable for timelines and quality of sub-projects within the bigger programs.
• Supports the preparations for internal group, project, and steering team meetings. Contributes to external collaborations and technical due-diligences by preparing presentation slides that effectively communicate project progress and outcomes.
• Takes responsibility for small organizational projects, e.g. ordering laboratory equipment and improving on laboratory safety.
• Documents procedures, results and conclusions timely and accurately in Electronic Lab Notebooks (ELN). Review and approve ELN experiments from colleagues to guarantee accuracy and consistency. Prepares and revises standard operating procedures (SOPs). Oversees the inventory for antibodies, enzymes, small molecules and cell lines.
• In case analytical or preparative instruments malfunction, identifies issues and troubleshoots.
• Assists with onboarding of new research associates. Supervises interns.
• What we are looking for:
• BSc/MSc degree in Biochemistry or Molecular biology.
• 2 - 4 years relevant experience in Biochemistry.
• Demonstrates a strong focus to laboratory work and a high attention to detail and strong experimental standards.
• Works closely with (senior) scientists, contributes to project progression, and communicates effectively within the team.