Scientist - Structural Informatics Infrastructure

The diffUSE Project is seeking a Scientist to join a multidisciplinary team to help build the infrastructure needed to host and distribute dynamic structural biology data. The diffUSE Project is an ambitious initiative designed to advance our understanding of protein dynamics by building the experimental methods, computational models, and global infrastructure needed to capture molecular motion at scale. Our goal is to establish dynamic structural biology as a foundational pillar of modern science, as transformative and indispensable as static structures have been.

This role will lead the development of standards and platforms that enable the community to deposit, validate, search, and leverage dynamic structural information at scale. The job will involve helping to architect the foundational infrastructure, including metrics and encoding, to make dynamic structural biology data as accessible, trustworthy, and impactful as the Protein Data Bank has been for static structures. You will work at the intersection of structural biology, data science, and community standards development to build an ensemble-aware, living database that evolves with algorithmic advances while maintaining scientific rigor and reproducibility.

This is a full-time position within the diffUSE Project, in-person at Radial, a division of the Astera Institute.