Scientist, DMPK

• Ph.D. in pharmaceutical sciences, pharmacology, chemical or biomedical engineering, or a related quantitative discipline with 0+ years of relevant experience; or exceptional non-PhD (Masters degree with 5+ years, or Bachelors degree with 10+ years of relevant industry experience in DMPK or quantitative pharmacology.
• Strong foundation in quantitative pharmacology and PK/PD modeling, with hands-on experience in non-compartmental and compartmental data analysis.
• Exposure to PBPK, population PK, or systems/mechanistic pharmacology modeling is a strong plus.
• Proficiency with modeling, simulation, and programming tools (e.g., Phoenix WinNonlin, Monolix, R).
• Solid understanding of ADME principles and the drug discovery and development process; knowledge of oligonucleotide therapeutics (e.g., siRNA, ASO) or other novel modalities is a plus.
• Demonstrates strong problem solving ability and adaptability, in and out of their comfort zone
• Detail-oriented with exceptional organizational skills, and the ability to handle multiple projects, and thrive in a fast-paced, team-oriented environment
• Has strong interpersonal skills to enable collaboration with cross-functional teams.

Possesses excellent verbal and written communication skills.

#LI-JR1

$110,400.00 - $165,600.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting.

Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education.

This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being.

We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match.

Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks.

We also offer generous family resources and leave.

Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases.

Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible.

Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people.

We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.