Research Associate

Roles & Responsibilities

• Report to the senior team leader.
• Work and collaborate daily with a group of in vitro assay biologists within the ADME department.
• Learn from and teach other group members to improve skills, increase productivity, and take part in cross-training of all ADME assays.
• Maintain a detailed laboratory notebook.
• Develop compound methods and collect data using LC-MS/MS and other modalities (HPLC, spectrophotometry, etc.)
• Conduct day-to-day testing of compounds in several cell/protein-based in vitro assays or experiments in a team-oriented environment.
• Analyze and interpret data using different software programs (Sciex Analyst, DiscoveryQuant, GraphPad prism, MS Excel, etc.)
• Prepare reports and communicate with collaborators and clients.
• Multitask, recognize problems, provide input to solutions, draft reports, and communicate results proficiently with clients and in lab meetings.
• Contribute to basic lab maintenance such as preparing buffers, cleaning, ordering, stocking, and follow-up.
• Communicate and work closely with other departments to finish collaboration projects in a timely manner.
• Offer drug discovery screening and IND filing support for multiple client-based projects
• Other duties as assigned

Education, Experience & Skills Required

• BS or MS in biology, chemistry, or related area.
• 2-4 years of related experience in the biotech, pharma or preclinical CRO industry. Working experience with LC-MS/MS, HPLC, bioanalytical studies preferred.
• Strong problem solving and troubleshooting skills with demonstrated ability to resolve complex situations that require a logical, analytical and methodical approach.
• Self-motivated to multitask, initiate projects, and work both independently and in a team environment to meet deadlines
• Excellent organization and planning skills with attention to detail.
• Committed to customer satisfaction and focused on the importance of quality.
• Excellent interpersonal and communication skills.
• Hands-on exposure to general biotech laboratory equipment. A preferred candidate will have a good understanding and knowledge of laboratory tools, techniques, methods, and underlying principles. Work experience in cell-culture or in an in vitro ADME/DMPK lab preferred but not required.
• A theoretical understanding of different ADME assays (solubility, microsomal stability, plasma and blood stability, plasma protein binding, permeability, CYP enzyme and transporter inhibition and substrate determination, etc.) preferred but not required.

Significant Safety or Working Considerations