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Principal Scientist, Flow Cytometry

Precision for Medicine

Frederick, USA

Senior

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Role Overview

The Principal Scientist will be instrumental in helping Precision achieve its goals of delivering exceptional services to Precision’s diverse, innovative and global biopharmaceutical clients. Working closely with the Senior Vice President, Lab Operations they will help implement the strategic scientific plan to support translational medicine research, primarily, but not solely, in the Immuno-Oncology and autoimmune/inflammatory space. Key components will be focused on, design and development of innovative qualified and validated immunophenotyping (including high content flow cytometry assays up to 31 markers, receptor occupancy assays, tetramer/dextramer assays as well as immunophenotyping flow based assays), and antigen specific (ELISpot/Fluorospot) or other custom cell based assays. The successful candidate will assist and be a resource for senior team members to design experimental plans and timelines, that match client specifications/requirements. They should and be able to communicate the plan and progress to the client, along with executing and reporting the work according to agreed timelines and under the appropriate regulations (GLP, CAP, CLIA etc.). A significant aspect of this job is the training and mentoring of more junior scientists and team members in bioservices both in laboratory techniques and in the analysis and presentation of data. The role will provide technical expertise to the laboratory as needed, as well as the expectation is that a large part of training is provided “hands on”.

Essential functions of the job include but are not limited to:

• Provide mentoring, coaching and training to Flow Laboratory team members, assist in setting priorities for lab work in collaboration with other team leaders

• Motivate team, share knowledge on FACS, participate in recruitment process and revenue forecasting

• Design and implement cell-based assays to meet client requirements; may include complex flow immunophenotyping assays, primary cell based assays.

• Write and implement standard operating procedures (SOPs) to perform assays to meet client requirements and the level of regulatory compliance needed

• Utilize current SOPs to perform cell assays such as flow immunophenotyping, ELISpot, and other custom cell based assays.

• Generate technical reports and other communications required to present data to clients

• Write posters and papers for submission to conference organizers and peer reviewed journals

• Write reviews and white papers

• On occasion, review and edit client proposals, contract/proposals as appropriate.

• Train scientific staff in the review and presentation of data; including client reports, posters and papers for peer reviewed journals

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Full Job Posting

Qualifications:

Minimum Required:
Must have a Ph.D. in life sciences or relevant field (preferably Immunology, Cellular Biology)
At least 8 years of full-time post-doctoral laboratory experience
Other Required:
Strong bench scientist skills around cell based assays. Hands on flow cytometry experience is required. Preferably with experience in ELISpot and other cell based assays. Core competencies of standard biology laboratory experience e.g. cell isolation, and primary cell based assays.
Experience with cell sorting, trouble-shooting and client relationships, alliance partnerships and timelines
Experience in validation/qualification of assays to CAP/CLIA/GLP or ISO guidelines
Strong organizational skills
Strong communication skills
Experienced technical report generation
The ability to see and differentiate between colors on the full color spectrum
Ability to lift and carry between 1-15 lbs.; Ability to lift up to 50 lbs. overhead with assistance; frequently required to sit, grasp, and use right/left finger dexterity; May be exposed to a cold freezer environment (Freezer temperatures range between -20oC -196oC)
Must be able to read, write, speak fluently and comprehend the English language
Preferred:
10-15+ years’ experience as CORE lab member with leadership role as direct manager to flow cytometry team
Industrial experience and/or management of outside collaborations is desirable
Experience with viral infections; cell culture and cell line derivation; nucleic acid (RNA & DNA) extraction from primary human samples; nucleic acid characterization by spectrophotometer, Agilent, and fluorescence-based detection
Any data provided as a part of this application will be stored in accordance with our Privacy Policy. For CA applicants, please also refer to our CA Privacy Notice.
Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.
If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at myHR@precisionmedicinegrp.com.
Recruitment Fraud Warning: Please be aware that fraudulent individuals and websites may impersonate Precision Medicine Group or its affiliates and attempt to obtain personal, financial, or banking information through fake job postings or employment offers. Precision Medicine Group will never request payment, banking details, or other sensitive financial information as part of the recruitment process. If you believe you have been targeted by a recruitment scam, we encourage you to report the incident to your local law enforcement authorities, consumer protection agency, or relevant cybercrime reporting organization in your country. Please also notify us at myHR@precisionmedicinegrp.com so we can investigate and take appropriate action.

Principal Scientist, Flow Cytometry

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