Postdoctoral Researcher
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About the Role
Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU; www.mbru.ac.
Key Skills for This Role
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Overview
Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU; www.mbru.ac.ae) is part of Dubai Health, the first integrated academic health system in the UAE.
Dubai Health seeks to strengthen Dubai as a global leader in health care, medical education, research, and scientific innovation, to enhance the capabilities of Dubai’s healthcare sector.
Dubai Health is managing and operating 54 sites, including 6 government hospitals, 26 ambulatory health centers, 20 medical fitness centers, Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), and Al Jalila Foundation.
Role Purpose
The Postdoctoral Research Fellow will lead computational research supporting therapeutic development programs, with a focus on antisense oligonucleotides (ASOs), RNA biology, and functional genomics.
The role involves multi-omics data analysis, integration of transcriptomic and genomic datasets, and development of computational pipelines to support target discovery, validation, and translational research initiatives.
Strategic Responsibilities
- Contribute to building machine learning models and computational strategy for therapeutic and functional genomics programs
- Build deep neural network-based models to ssupport data-driven decision making for target prioritization and validation
- Collaborate with wet lab teams to integrate experimental and computational workflows
- Identify and implement advanced bioinformatics tools and pipelines
Core Responsibilities
- Building machine learning models using multi-omics data for neuro-oncology projects
- Analyze RNA-seq, long-read sequencing (PacBio), and other omics datasets
- Develop and maintain bioinformatics pipelines for transcriptomics and genomics
- Perform differential expression, pathway analysis, and functional annotation
- Integrate multi-omics datasets (genomics, transcriptomics, proteomics where applicable)
- Support ASO target identification and validation through data-driven approaches
- Collaborate with lab scientists to interpret experimental results
- Maintain reproducible workflows (R/Python, workflow managers)
- Contribute to publications, grants, and scientific outputs
- Present findings internally and at scientific meetings
- Participate in teaching and education-related activities within the College of Medicine, MBRU.
Community Service
- Seeks and develops relationship with suitable external partners in order to raise the profile of the College and the University.
- Provides opportunities for assisting professional colleagues to maintain and enhance their skills by offering Continuing Professional development in their specialty.
Self-Management Responsibilities
- Defines performance goals at the start of the year in discussion with the reporting manager and ensures that the goals are monitored and achieved during the year.
- Takes ownership of his/her own learning agenda by identifying development needs in consultation with the reporting manager and working towards bridging the gaps through various means which go beyond just training.
- Understands the competencies relevant to his/her role and works towards displaying as well as developing these effectively.
- Keeps abreast of relevant professional/industry developments, new techniques and current issues through continued education and professional networks.
Minimum Qualifications
- PhD in Bioinformatics, Computational Biology, Genomics, or related field
- Strong experience in RNA-seq and transcriptomic data analysis
- Proficiency in R and/or Python
- Experience with NGS data analysis pipelines
- Ability to work independently and design computational workflows
Preferred Qualifications
- Experience with long-read sequencing (PacBio, Iso-Seq)
- Exposure to therapeutics, RNA biology, or functional genomics
- Familiarity with multi-omics integration
- Experience working with clinical or translational datasets
- Publication record in relevant field
- Written and spoken English is essential, Arabic is preferred
- Years of Experience:
- PhD in machine learning or artificial intelligence, bioinformatics, computational biology, genomics, or related field or a related field from an accredited institute/college/university.
- Minimum 1 – 2 years of relevant post-doctoral experience.
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