Lead Scientist - Translational Pathology

Bangalore, KA, IN, 560099

JOB DESCRIPTION

Designation: Lead Scientist Job Location: Bangalore Department: Pathology/IHC

About Syngene Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- a strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose (1-2 Lines): This position requires the person to independently perform routine histopathology techniques including sectioning, embedding, grossing, and H&E staining with high precision and adherence to quality standards.

Key Responsibilities: • Independently perform routine histopathology techniques including sectioning, embedding, grossing, and H&E staining with high precision and adherence to quality standards. • Execute monoplex chromogenic automated IHC assays with full compliance to internal standardization guidelines and ensure consistency in results. • Operate and maintain automated laboratory equipment (Autostainer, cover slippers, digital scanners) as per Work Instructions, ensuring optimal performance and troubleshooting as needed. • Manage digital workflows by scanning slides accurately using digital slide scanners, labeling, and maintaining a comprehensive whole-slide image repository. • Perform and support advanced cell culture techniques independently, ensuring sterility and accuracy in experimental setups. • After initial orientation by senior image analysts, independently build robust, specific, and validated algorithms for quantitative image analysis to support research and diagnostic workflows. • Maintain meticulous documentation of all laboratory processes, including electronic lab notebooks (ELN), and ensure compliance with regulatory and internal standards. • Oversee reagent inventory and slides/block management, including tracking inflow, re-embedding blocks when required, monitoring reagent expiry, and maintaining accurate consumption records. • Contribute to SOP and Work Instruction development and periodic reviews, ensuring continuous improvement and alignment with best practices. • Provide technical guidance and support to junior team members, fostering knowledge-sharing and operational excellence. • Perform additional laboratory duties as assigned, demonstrating flexibility and ownership of tasks.

Educational Qualification: Bachelor’s/ Master’s in biology / Biotechnology / Biochemistry or Equivalent degree in Lifesciences

Technical/functional Skills: (Maximum 4-6 Points) • Experienced in design and development of monoplex IHC assays • Experience in working on diverse IHC Autostainer instruments and troubleshooting • Experience with routine histopathological techniques is required. • Experience in handling digital scanners and use of digital pathology software platforms. • Having worked with preclinical and clinical samples will be a plus • Experience of working in a regulated laboratory setting (CAP/NABL or other GxP environment) is good to have.

Behavioral Skills: • Ensure completion of experiments and generate accurate and reproducible data from experiments. • Good oral and written communication and presentation skills to work in a multi-disciplinary team

Equal Opportunity Employer: It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.