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gRNA Process Development Scientist
Eurofins
Boston, USA
Full-time
Mid-Senior
Onsite
$32.00 to $41.00 per hour
Discovered 1 weeks ago
gRNA process developmentOligonucleotide synthesisOligonucleotide purificationSolid-phase synthesisHPLC/UHPLCUV-Vis
Free
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gRNA process developmentOligonucleotide synthesisOligonucleotide purification
Role Overview
Join the gRNA process development team and contribute to drug substance process development for programs in clinical development.
Develop manufacturing processes and controls through gRNA synthesis, purification, and characterization.
Key Skills for This Role
gRNA process developmentOligonucleotide synthesisOligonucleotide purificationSolid-phase synthesisHPLC/UHPLCUV-Vis
Full Job Posting
Role Overview
Join the gRNA process development team and contribute to drug substance process development for programs in clinical development.
Develop manufacturing processes and controls through gRNA synthesis, purification, and characterization.
Responsibilities
- Execute solid-phase synthesis and purification experiments for process development, scale-up, and manufacturing transfer.
- Perform routine analytics including HPLC and UV-Vis.
- Prepare buffers, reagents, and stock solutions using established recipes and SOPs.
- Compile and present data to team members and key stakeholders.
- Maintain laboratory notebooks, order materials, maintain equipment, and support troubleshooting.
- Uphold laboratory safety standards.
Minimum Required Qualifications
- Bachelor’s or master’s degree in chemistry, chemical engineering, biochemistry, or a related field, plus at least 2 years of relevant laboratory industry experience.
- Experience with oligonucleotide synthesis and purification equipment.
- Experience operating Akta chromatography systems, Agilent U/HPLC, gel electrophoresis, and NanoDrop.
- Experience with tangential flow filtration is required.
- Ability to follow established SOPs for routine analytical support.
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