Associate Scientist III, CMC Process Development

The Associate Scientist III in the Process Development Chemistry Group focusing on oligonucleotide analysis and synthesis development. This is an ideal position for an individual with an organic or biological chemistry background who has an interest in projects related to novel technology in synthesis and purification of oligonucleotides and bioconjugates.

Responsibilities

Independently provide accurate analytical results in support of new and on-going projects with a focus on process characterization.

Perform analytical techniques, such as HPLC, UV/Vis, LC/MS, etc.

Handle, analyze and characterize chemicals, pharmaceuticals, and related organic molecules.

Analyze data/results and interpret outcome of experiments and independently propose appropriate follow-up.

Calibrate, maintain, and troubleshoot all analytical equipment.

Work closely with senior chemists on development of new synthetic approaches to desired compounds with an eye toward large-scale synthesis

Cooperate with other chemists in the group in preparation of complex organic constructs

Analyze small-molecule and macromolecular targets using standard methods

Maintain a well-documented laboratory notebook

Prepare documentation for transfer of new technologies to the Manufacturing group

Track progress against project timelines, generate regular status updates, and communicate progress and issues to management, including presentation of findings at team meetings

Coordinate delivery of materials both internally and externally